Vitae Pharmaceuticals (NASDAQ: VTAE) and Cesca Therapeutics (NASDAQ:KOOL) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, earnings, analyst recommendations, valuation, institutional ownership, dividends and risk.

Profitability

This table compares Vitae Pharmaceuticals and Cesca Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Vitae Pharmaceuticals -318,350.20% -53.70% -49.85%
Cesca Therapeutics -84.29% -30.45% -21.65%

Institutional & Insider Ownership

72.6% of Vitae Pharmaceuticals shares are held by institutional investors. Comparatively, 3.0% of Cesca Therapeutics shares are held by institutional investors. 14.8% of Vitae Pharmaceuticals shares are held by insiders. Comparatively, 3.9% of Cesca Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Valuation & Earnings

This table compares Vitae Pharmaceuticals and Cesca Therapeutics’ revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Vitae Pharmaceuticals N/A N/A N/A ($1.92) -10.94
Cesca Therapeutics $14.52 million 2.06 -$29.09 million ($0.91) -3.30

Vitae Pharmaceuticals has higher earnings, but lower revenue than Cesca Therapeutics. Vitae Pharmaceuticals is trading at a lower price-to-earnings ratio than Cesca Therapeutics, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a summary of current ratings and target prices for Vitae Pharmaceuticals and Cesca Therapeutics, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vitae Pharmaceuticals 0 0 0 0 N/A
Cesca Therapeutics 0 1 0 0 2.00

Summary

Cesca Therapeutics beats Vitae Pharmaceuticals on 6 of the 8 factors compared between the two stocks.

Vitae Pharmaceuticals Company Profile

Vitae Pharmaceuticals, Inc. is a biotechnology company. The Company is focused on discovering and developing small molecule drugs for diseases. It is engaged in developing a portfolio of product candidates through Contour, its structure-based drug discovery platform. The Company’s product candidates include VTP- 43742 for the treatment of psoriasis, as well as multiple other autoimmune disorders. The Company completed approximately two Phase I studies with VTP-43742. Its VTP-38543, a second product candidate is in a Phase IIa proof-of-concept clinical trial for the treatment of atopic dermatitis. Its VTP-36951 is for the treatment and prevention of Alzheimer’s disease, or Alzheimer’s. VTP-43742, the Company’s wholly owned clinical candidate in an on-going Phase IIa proof-of-concept trial in psoriasis, is an orally active small molecule inhibitor of Retinoic acid-receptor (RAR)-Related Orphan Receptor gamma-t (RORgt) activity for the treatment of various autoimmune disorders.

Cesca Therapeutics Company Profile

Cesca Therapeutics Inc. is clinical-stage biotechnology company. The Company develops and markets integrated cellular therapies and delivery systems. The Company is engaged in developing and manufacturing of automated blood and bone marrow processing systems that enable the separation, processing and preservation of cell and tissue therapy products. The Company focuses on the business of research, development and commercialization of autologous cell-based therapeutics for use in the regenerative medicine industry. The Company’s therapeutic development initiatives focuses on the fields of cardiovascular medicine and orthopedic regeneration. The Company offers a range of products, such as SurgWerks System, CellWerks System, AutoXpress System (AXP), MarrowXpress System (MXP), BioArchive System, and manual bag sets for use in the processing and cryogenic storage of cord blood.

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